Clinical Manifestattions of Condyloma Acuminata

Condyloma acuminata incubation period lasts between 1-8 months (average 2-3 months). HPV enters the body through the micro-lesions on the skin, so condyloma acuminatum often arise in areas prone to trauma during sexual intercourse.

The disease is mainly found in the folds of damp, for example in the area of ​​the external genitalia. In men a predilection in the perineum and around the anus, the coronary sulcus, glans penis, the external urethral opening, body and base of the penis. In women in the vulva and surrounding area, vaginal introitus, sometimes on the lower portion of the uterus. In women who spend a lot of fluor albus or women who are pregnant, faster growth of the disease.

For clinical purposes condyloma acuminatum divided into 3 types:
1. Acuminatum Form
Mainly found in the folds and moist. Looks stemmed vegetation protruding surfaces such as a finger. Some warts may coalesce to form larger lesions that look like cauliflower. Large lesions is often found in women with fluorine albus, in pregnant women, and the state of impaired immunity.

2. Papules Form
Lesions form of papules usually found in areas with keratinization perfect, like the penis, vulva, lateral part, perianal and perineal area. Disorder in the form of papules with a smooth and slippery surface, multiple and dispersed discretely.

3. Flat Form.
  Clinically, the lesion is seen as a form of macular or even not at all appear to the naked eye (subclinical infection), and will look after the acetic acid test. In this case the use of colposcopy is helpful. However keep in mind that there are no clear boundaries between the three forms, and often encountered earlier, intermediate forms. In addition to the above three clinical forms, found also other clinical forms that have been known to be associated with malignancy in the genitalia, namely:
a. Giant condyloma Buschke-Lowenstein
This form is classified as squamous cell carcinoma with low-grade malignancy. The relationship between condyloma acuminatum with giant condyloma known by the discovery of HPV type 6 and type 11. The location is the most frequent lesion on the penis and sometimes the vulva and anus. Clinical condylomata appear as large, locally invasive and metastasize. Histologically, not unlike the giant condyloma, condyloma acuminatum. Giant condyloma is generally refractory to treatment
b. Papulosis Bowenoid
Clinically form reddish brown lichenoid papules and plaques can be confluented. There is also a form of macular erythematous lesions and lesions that resemble leukoplakia or subclinical lesions. Generally, multiple lesions and sometimes pigmented. Bowenoid papulosis lesion surface is usually smooth or only slightly papilomatosa. Bowen disease histopathologic picture is similar to the core group, diskeratotic giant cells, and as atypical mitotic. In the course of the disease, Bowenoid papulosis rarely become malignant and tends to regress spontaneously


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