Therapy for Condyloma Acuminata

1. Chemotherapy

a. Podophyllin

25% podophyllin tincture. The surrounding skin is protected with petroleum jelly or paste, to avoid irritation, after 4-6 hours and then washed. If there is no cure, it can be repeated after 3 days. Every administrated, do not exceed 0.3 cc because it will be absorbed and toxic. Symptoms of toxicity are nausea, vomiting, abdominal pain, respiratory irritation, and skin with cold sweat. Can also occur bone marrow suppression with thrombocytopenia and leukopenia. In pregnant women should not be given because of fetal death can occur. Also, please do not used for the treatment of lesions in the vagina and cervix because this drug can be absorbed so that the toxic and may cause carcinoma.

Clinical Manifestattions of Condyloma Acuminata

Condyloma acuminata incubation period lasts between 1-8 months (average 2-3 months). HPV enters the body through the micro-lesions on the skin, so condyloma acuminatum often arise in areas prone to trauma during sexual intercourse.

Pathophysiology of Condyloma Acuminata

Condyloma acuminata can be caused contact with patients infected with HPV. Until now more than 100 known types of HPV, which often causes condyloma acuminata namely HPV types 6 and 11 is entered through a micro-lesions on the skin, usually in the genital area and penetrate the skin, causing the surface epithelial abrasion. 
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