25% podophyllin tincture. The surrounding skin is protected with petroleum jelly or paste, to avoid irritation, after 4-6 hours and then washed. If there is no cure, it can be repeated after 3 days. Every administrated, do not exceed 0.3 cc because it will be absorbed and toxic. Symptoms of toxicity are nausea, vomiting, abdominal pain, respiratory irritation, and skin with cold sweat. Can also occur bone marrow suppression with thrombocytopenia and leukopenia. In pregnant women should not be given because of fetal death can occur. Also, please do not used for the treatment of lesions in the vagina and cervix because this drug can be absorbed so that the toxic and may cause carcinoma.